Exiguobacterium: A Clinical Aspect
Louise Jae Dumdumaya
Department of Biology
Faculty Supervisor: José R. de la Torre
Exiguobacterium is a Gram-positive bacilli that is not commonly known to associate with human infections, rather known to grow in extreme environments. Antibiotic resistance is a recurring issue that arises in microbiology, both environmentally and clinically. This study aims to discuss the impact of antibiotic resistance in Exiguobacterium as well as evaluating challenges in a clinical setting. Potential peer-reviewed articles from databases such as the National Library of Medicine had been utilized to focus on Exiguobacterium genetic adaptations of the bacteria and clinical implications such as skin infections, while also discussing mechanisms of antibiotic resistance. Impacts of lateral gene transfer and treatments for infections in the body. Observing the genome sequence in antibiotic resistance can also be a potential method. Overall research indicated Exiguobacterium had resistance to a multitude of antibiotics like tetracycline and erythromycin. Skin infections such as pneumonia and bacteremia were also discovered to be from a certain strain of Exiguobacterium. A presence of plasmid-encoded resistance and lateral gene transfer had been a potential inquiry for multiple drug resistance use. In terms of clinical cases, it still seems to be unknown as to what guidelines can be taken towards Exiguobacterium. Though further research must be made for resistance mechanisms in Exiguobacterium, solutions can be further improved through diagnostics and research on certain cases that pertain to a clinical route of things.